After 21 years of not seeing their favorite San Francisco family on television, fans of "Fuller House" are now all fired up to watch the premiere of the sitcom.

Inspired by the original series that last aired in 1987, "Fuller House" will center on the life of D.J. Tanner-Fuller, now a widow, who has to juggle her career as a veterinarian with her being a mother of three sons.

The series will focus on the lives of the kids and how D.J. and Kimmy come to grips with their parenting problems.

Spoilers of the "Full House" spinoff show that D.J. will now have to swim with the tide without her husband Tommy but with her sister Stephanie and best friend Kimmy moving in to help her out with her three sons, Jackson, Tommy Jr. and Max.

In the new series, Stephanie is an aspiring musician while Kimmy is divorced and is pursuing her event-planning career while raising her rebellious teenage daughter Ramona.

In an interview with E! News, Sonia Nicole who plays Ramona in the reboot said it was fun for her to be part of the show and "keep the legacy going."

Aside from the fresh faces, fans will also get to see some of their much-missed "Full House" characters in "Fuller House," including Jesse, Danny, Steve and Becky.

Spoilers also reveal that the spinoff even offers a tinge of romance, with D.J. and Steve fondly bear-hugging each other in the trailer. This got fans wondering if D.J. and her ex-love interest are rekindling their romance now that the matriarch of the Tanner family is already a widow.

"Fuller House" is set to premiere on Netflix on Feb. 26.